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Installing consistent symptomatic and you can biomarker research standards would be necessary for future meta-analyses and systematic trials exploring directed treatments to own FS. Drawn along with her, these types of findings service an excellent multidisciplinary and you may individualized way of FS administration, adding metabolic and inflammatory profiling for the symptomatic and you may therapeutic procedures. Later, the newest integration out of biomarker research with longitudinal clinical variables you are going to raise chance stratification and you can individualized therapy, broadening government past traditional orthopedic treatments. That it meta-study aids the new conceptualization away from FS as the a good systemic condition influenced by metabolic and inflammatory dysregulation, giving multiple actionable information to have medical practice.

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Inside article alternatives procedure, a maximum of 438 articles was recognized in the certain digital databases. Just after removing copies, 109 blogs had been assessed by the its titles and you can abstracts to evaluate once they came across the fresh introduction conditions. Immediately after complete-text discovering, ten articles were excluded because the clients on the training had each other FS and you may cancers.

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